PTSD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Women between the ages of 18 and 40 (biologically female)
- People who are still having menstrual cycles (pre-menopausal), based on self-report
- People who have experienced trauma, with or without a diagnosis of PTSD
- People who have been diagnosed with major depression
- People with certain other mental health conditions may also be eligible, including anxiety disorders, bipolar disorder (without psychotic features), mild to moderate traumatic brain injury, or borderline personality disorder
- People who are willing and available to take part in all study activities for the full duration of the trial
- People already taking psychiatric medications may be eligible, as long as their medications have not changed in the past 3 months
- For those in the PTSD groups: a confirmed PTSD diagnosis meeting specific symptom criteria assessed through a structured clinical interview (confirm with trial site)
- Any over-the-counter medications must be paused for 24 hours before each study visit
Who may not be able to join:
- People who are not biologically female
- People currently using hormone replacement therapy
- People who are pregnant, breastfeeding, or planning to become pregnant during the study
- People currently using any form of hormonal contraception (such as the pill, patch, or hormonal IUD)
- People with certain medical conditions, including high blood pressure, diabetes, heart disease, vascular disease, high cholesterol, autonomic dysfunction, serious systemic illness, or gastrointestinal disorders
- People currently using illicit drugs, or those with a history of illicit drug use who have not had at least 6 months of non-use
- People who drink more than 2 alcoholic drinks per day
- People taking certain medications that affect blood vessels or the cardiovascular system, including blood pressure medications (such as beta blockers, calcium channel blockers, or ACE inhibitors), corticosteroids, nitrates, hydralazine, or thyroid medications (confirm full list with trial site)
- People with psychotic disorders or dissociative disorders
- People who are unwilling or unable to avoid nicotine use for at least 12 hours before study visits
- People with gastrointestinal conditions such as irritable bowel syndrome or coeliac disease
- People with a food allergy related to dietary nitrates or nitrate-containing foods
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Ida-Arlaine Fonkoue, MD, PhD, MsCR, University of Minnesota
Phone: 612-626-2520
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Flow Mediated Dilation (FMD)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.