Phase 2 Cystic Fibrosis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 80 years old at the time of signing the consent form
• You have a history of symptoms consistent with non-cystic fibrosis bronchiectasis, such as a long-term productive cough and/or repeated chest infections
• You have had at least 2 chest infection episodes in the past 12 months that required a doctor to prescribe antibiotics (by mouth or through a drip) for 5 or more days
• A CT scan of your chest has confirmed that you have bronchiectasis
• Your CT scan shows a minimum level of disease severity based on a specific scoring system (confirm with trial site)
• You are currently producing mucus/phlegm and have been doing so regularly for at least 3 months within the past year
• Your lung function test (a breathing test measuring airflow) shows your lungs are working at least 30% of the expected normal level after using a bronchodilator (an inhaler that opens the airways)

Who may not be able to join:

• Your main diagnosis is COPD caused by smoking, or asthma, as decided by the doctor running the trial
• You have been diagnosed with a specific type of allergic lung condition caused by fungi (confirm with trial site)
• You have an active lung infection caused by a group of bacteria called non-tuberculous mycobacteria, or you have not completed treatment for such an infection
• Your bronchiectasis is caused by cystic fibrosis, a specific immune deficiency condition, a genetic lung condition, or a condition affecting the tiny hairs in your airways (confirm with trial site)
• You have had a serious episode of coughing up blood that required medical treatment or a blood transfusion
• You are currently a smoker
• You have a known or suspected problem with your immune system, including a history of certain serious or unusual infections, or infections that keep coming back more than expected
• You have an active autoimmune disease (where the immune system attacks the body) or are taking medication to suppress the immune system for such a condition, including conditions like lupus, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, or psoriasis, among others

Important: Always verify eligibility with the trial site directly before applying.