Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 55 years old.
• People with a BMI in the healthy range (18.5–24.9) or above 30 (Part 1 of the trial), or people with a BMI above 30 (Part 2 of the trial).
• Women who are not pregnant and not planning to become pregnant during the trial.
• Women who have not yet gone through menopause.
• People with no more than one risk factor related to blood pressure, blood sugar, triglycerides, or HDL ("good") cholesterol levels.
• People who have not been diagnosed with a serious heart or metabolic condition, such as cardiovascular disease or type 2 diabetes.
• People who have not been diagnosed with a long-term inflammatory or digestive condition, such as rheumatoid arthritis or inflammatory bowel disease.
• People who do not regularly take anti-inflammatory medications (more than twice a week), or who are able to stop taking them for three days before each study visit.
• People who have not taken antibiotics or probiotics in the past month.
• People who do not take cholesterol-lowering medications (such as statins), blood sugar-lowering medications (such as metformin), or blood pressure medications.
• People who do not take weight-loss medications (such as Ozempic or Wegovy).
• People who have not had surgery that changed the structure of their stomach or digestive tract, such as a gastric sleeve or gastric bypass.
• People who do not use tobacco products or illegal drugs.
• People who do not have a pacemaker.
• People who have no dietary restrictions that would prevent them from eating a meal provided by the study (for example, people who do not follow a vegan, vegetarian, or gluten-free diet, and have no relevant food allergies).
• People who are able to lie flat and still in a darkened room for at least 10 minutes (required for a blood vessel measurement).

Who may not be able to join:

• People outside the age range of 18 to 55 years.
• People whose BMI does not fall within the required ranges for either part of the trial.
• Women who are pregnant or planning to become pregnant.
• Women who have gone through menopause.
• People with two or more risk factors related to blood pressure, blood sugar, triglycerides, or HDL cholesterol.
• People who have been diagnosed with a serious heart or metabolic condition, such as cardiovascular disease or type 2 diabetes.
• People who have been diagnosed with a long-term inflammatory or digestive condition, such as rheumatoid arthritis or inflammatory bowel disease.
• People who regularly take anti-inflammatory medications more than twice a week and are unable to pause them for three days before a study visit.
• People who have taken antibiotics or probiotics within the past month.
• People who currently take cholesterol-lowering, blood sugar-lowering, or blood pressure medications.
• People who currently take weight-loss medications such as Ozempic or Wegovy.
• People who have had surgery that altered the stomach or digestive tract, such as a gastric sleeve or gastric bypass.
• People who use tobacco products or illegal drugs.
• People who have a pacemaker.
• People with dietary restrictions that would prevent them from eating the meal provided during the study, including vegans, vegetarians, those on a gluten-free diet, or those with relevant food allergies.
• People who are unable to lie flat and still in a darkened room for at least 10 minutes.

Important: Always verify eligibility with the trial site directly before applying.