Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT07574684 Sponsor: Ain Shams University Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT07574684
Not Yet Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have been diagnosed with Stage III or Stage IV non-small cell lung cancer (a type of lung cancer) that cannot be removed by surgery
  • You are generally able to carry out some daily activities, though you may have some limitations due to your illness (confirm with trial site)
  • Your cancer does not have certain specific genetic changes, or those genetic changes are not yet known
  • You are planned to receive a chemotherapy combination (called platinum doublets), with or without immunotherapy medicines
  • Your blood counts, liver, and kidney are working well enough to meet specific health thresholds (confirm with trial site for exact values)

Who may not be able to join:

  • You have had an allergic reaction to a supplement called alpha lipoic acid in the past
  • You are currently pregnant or breastfeeding
  • You are taking iron supplements that may interact with alpha lipoic acid
  • You are taking thyroid medications that may interact with alpha lipoic acid
  • You have severe memory problems, a neurological condition such as dementia or Alzheimer's disease, or a severe mental health condition that would make it difficult to follow the study requirements
  • You have uncontrolled heart disease, such as a recent heart attack or heart failure
  • You have high blood pressure that cannot be controlled with medication
  • You have cancer that has spread to your brain

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 June 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
20 April 2026
Est. completion
1 January 2027

Primary endpoints

1. Clinical Benefit Rate (CBR); 2. Tumor Response Rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov