Phase 3 Obesity Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People with a Body Mass Index (BMI) of 25 or higher at the time of screening (BMI is a measure of body weight relative to height)
- People who have already lost 10% or more of their body weight while taking a weekly GLP-1 RA medication (a type of weight management injection)
- People whose body weight has been steady and not changing significantly
- People who have been taking their GLP-1 RA medication at the same dose for a consistent period
- People who have been tolerating their GLP-1 RA medication without ongoing stomach or digestive problems
- Women who are using an accepted form of contraception
- People who are willing to follow all trial procedures for the full length of the trial
Who may not be able to join:
- People whose weight condition is caused by another hormonal or gland-related disorder, such as Cushing's syndrome
- People who have previously had, or are planning to have, surgery, an endoscopic procedure, or a medical device implanted to treat their weight
- People with a history of cancer
- People who have Type 1 or Type 2 diabetes
- People who have a personal or family history of a specific type of thyroid cancer called medullary thyroid cancer
- People who have previously taken part in a clinical trial involving a medicine called Maridebart Cafraglutide
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: MD, Amgen
Phone: 866-572-6436
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Percent Change from Baseline in Body Weight at Week 68
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.