Phase 3 Head and Neck Cancer Trial, Recruiting NCT07580300 Sponsor: Oslo University Hospital Condition: Head and Neck Cancer
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Phase 3 Head and Neck Cancer Trial, Recruiting

NCT07580300
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing and able to sign a consent form to take part in the study
  • You are 40 years of age or older
  • You have been diagnosed with a specific type of cancer called squamous cell carcinoma, confirmed by a tissue or cell sample, located in the mouth, throat, voice box, or lower throat area
  • You are scheduled to receive standard radiotherapy with the goal of curing your cancer, either on its own, after surgery, or alongside a chemotherapy drug called cisplatin
  • You are generally well enough to carry out most daily activities (your doctor will assess this)
  • You are able to complete questionnaires and follow the study procedures
  • You are able to answer questionnaires in Norwegian or English
  • You are willing to travel to Oslo or Bergen for proton therapy if you are placed in the experimental treatment group

Who may not be able to join:

  • You have an early-stage cancer of the vocal cords that has not spread to nearby lymph nodes or other parts of the body
  • You have a type of cancer affecting the back of the nose/upper throat, the nose and sinuses, or the salivary glands in the head and neck area
  • Your cancer has spread to other parts of the body (distant spread)
  • You have previously had radiotherapy to the head or neck area
  • You have a pacemaker or an implanted defibrillator (a device that regulates your heartbeat)
  • You have had another cancer in the last 5 years — though certain early-stage skin cancers and low-risk early-stage prostate cancer that were fully removed may not apply (confirm with trial site)
  • You weigh more than 150 kg, due to equipment weight limits
  • You have a serious or unstable medical or mental health condition that the trial doctor believes could affect your safety or ability to take part (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Hanne Eide, MD PhD, Oslo University Hospital

Phone: 004722934000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
28 April 2026
Est. completion
28 April 2030

Where this trial is recruiting

🇳🇴 Norway

Primary endpoints

The combined burden of patient-reported dysphagia, xerostomia, pain and speech measured as the area under the curve (AUC) with EORTC QLQ-H&N43 at baseline, end of treatment, 3-, 6- and 12-months following radiotherapy.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov