Phase 4 Interstitial Lung Disease Trial, Not Yet Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with rheumatoid arthritis (RA) based on standard medical criteria.
• A special lung scan (called an HRCT) has shown that you have a type of lung scarring or inflammation called interstitial lung disease (ILD), affecting at least 20% of your lungs, and other causes such as infection or fluid buildup have been ruled out.
• Your lung function tests show that your lungs are not working at full capacity — specifically, your breathing capacity or ability to absorb oxygen is below certain levels.
• If you are currently taking steroid medication (such as prednisone), you have been on a low, stable dose of no more than 10 mg per day for at least 4 weeks before the study starts.
• If you are currently taking a type of disease-modifying medication (called a csDMARD), you have been on a stable dose for at least 4 weeks before the study starts.
• You are willing and able to give written consent and attend all required study visits and follow-up appointments.

Who may not be able to join:

• You have another autoimmune disease in addition to rheumatoid arthritis.
• You have a serious, uncontrolled medical condition affecting a major organ that the study doctor believes would put you at too much risk.
• You have had a cancer diagnosis within the past 5 years.
• You are currently pregnant, breastfeeding, or planning to become pregnant or breastfeed during the study.
• You have a known allergy or sensitivity to any of the study medications (tocilizumab, telitacicept, or methotrexate) or their ingredients.
• You currently have an active hepatitis B, hepatitis C, tuberculosis, or shingles infection, or you have had a serious infection requiring hospital care or IV antibiotics within the past 12 weeks.
• Your blood protein levels (albumin or IgG antibodies) are very low (confirm with trial site).
• Certain liver or kidney function blood test results are outside of acceptable ranges (confirm with trial site).
• You have taken part in another clinical trial involving a treatment within the past 4 weeks.
• You are unable to complete the lung function tests or other assessments required by the study.
• The study doctor has any other concern that makes participation unsuitable for you.

Important: Always verify eligibility with the trial site directly before applying.