Phase 4 Endometrial Cancer Trial, Recruiting NCT07645625 Sponsor: University Medical Center Groningen Condition: Endometrial Cancer
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Phase 4 Endometrial Cancer Trial, Recruiting

NCT07645625
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For the main observation group:

  • You have cervical cancer that has come back, spread to other parts of the body, or keeps returning, and you are currently being treated or about to start treatment with a drug called pembrolizumab (either alone or combined with other medicines)

For the early stopping group (in addition to already being in the main observation group):

  • You were already enrolled in the main observation group and a decision has been made to stop pembrolizumab for one of these reasons: your cancer fully disappeared after at least 8 treatment cycles; you had a serious immune-related side effect (confirm with trial site for exact grading); you personally prefer to stop due to ongoing or difficult-to-manage side effects; or your cancer partially shrank after at least 8 treatment cycles
  • You are willing and able to stop taking pembrolizumab (you may or may not also stop another medicine called bevacizumab at the same time)

Who may not be able to join:

  • You have had another type of cancer (other than cervical cancer) that needed active treatment within the last 2 years — though some exceptions apply, such as certain skin cancers or pre-cancerous conditions that were successfully treated (confirm with trial site)
  • You have personal, mental health, family, social, or location-related circumstances that might make it hard to follow the study schedule, attend check-up appointments, have scans done, or fill out questionnaires

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: M. Jalving, University Medical Center Groningen

Phone: +31 50 361 2821

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
11 May 2026
Est. completion
1 May 2030

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Evaluate the progression-free survival (PFS) and compare to the KEYNOTE-826 trial

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov