Phase 2 Myasthenia Gravis Trial, Recruiting NCT07673744 Sponsor: TG Therapeutics, Inc. Condition: Myasthenia Gravis
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Phase 2 Myasthenia Gravis Trial, Recruiting

NCT07673744
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Myasthenia Gravis (MG).
  • You are eligible to receive the study drug efgartigimod based on your country's approved guidelines, confirmed by a blood test at the start of the study.
  • Your MG symptoms are measured using a specific scoring system (MG-ADL), and your score falls within a certain range that shows a meaningful level of difficulty with daily activities (confirm with trial site for exact score details).

Who may not be able to join:

  • You have another active immune system disease (such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, Sjögren's syndrome, or scleroderma) or an immune deficiency condition, whether inherited or caused by medication.
  • You have previously tried a similar type of treatment (called an FcRn treatment) and it either did not work for you or caused safety concerns.
  • You have ever received certain specific treatments that affect your immune system, including B-cell depleting therapies, alemtuzumab, total lymphoid irradiation, bone marrow transplant, T-cell vaccination therapy, or natalizumab.
  • You have seriously reduced function in one or more of your major organs (confirm with trial site).
  • You have had a severe or life-threatening allergic reaction to any of the medications used in this trial, including the study drugs or required pre-treatment medications.
  • You are unwilling or unable to follow the study procedures and required follow-up visits.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 1-877-575-8489

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
TG Therapeutics, Inc.
Registry
ClinicalTrials.gov
Start date
30 July 2026
Est. completion
1 July 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Time to Onset of a Clinical Worsening Event

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov