Bladder Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People whose doctors estimate they have a life expectancy of 10 years or more based on their biological age
• People who have not previously had any prostate treatments, such as laser surgery, TURP (a procedure to clear a blocked urethra), or focal therapy (targeted tumour treatment)
• People who have not had radiation therapy to the pelvis or prostate
• People who have not had previous surgery on the abdomen or rectum
• People who have not had hormone therapy (androgen-deprivation therapy) to reduce testosterone before this point
• People who have not had a stroke or reduced blood flow to the brain that left lasting neurological effects
• People who do not have a neurological condition such as Parkinson's disease
• People who have had a prostate biopsy taking at least 12 samples from both sides of the prostate, using MRI-guided and systematic methods
• People whose PSA blood test result is 15 ng/mL or below, and whose prostate is 80 mL in size or smaller
• People whose biopsy results show a cancer grade in the ISUP 1–3 range (also described as Gleason scores 3+3, 3+4, or 4+3)
• People whose biopsy does not show certain more aggressive cancer patterns (specifically Gleason pattern 5, intraductal, cribriform, or neuroendocrine carcinoma)
• People who have had a specific type of prostate MRI scan (required if the biopsy Gleason score is 3+4 or higher)
• People whose staging investigations show no signs that the cancer has spread to other parts of the body

Who may not be able to join:

• People who do not meet any one of the inclusion criteria listed above
• People who decline the trial procedure and instead choose to proceed with the standard robotic-assisted surgery as recommended under European urology guidelines

Important: Always verify eligibility with the trial site directly before applying.