Early Phase 1 PTSD Trial, Recruiting NCT07710417 Sponsor: Laureate Institute for Brain Research, Inc. Condition: PTSD
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Early Phase 1 PTSD Trial, Recruiting

NCT07710417
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have experienced trauma connected to their work, and who either score at or above a certain level on a standardised stress symptom checklist (PCL-5), meet criteria for full or partial PTSD on a clinical interview, OR show evidence of work-related trauma exposure alongside significant moral distress, difficulty functioning in daily life, or high perceived stress levels (as measured by specific assessment tools)
  • People who work as first responders or emergency medical personnel
  • People who are able to read, speak, and understand English
  • People who are able to give their own informed consent to participate

Who may not be able to join:

  • People with a history of neurological conditions
  • People with skin conditions or open wounds
  • People who have a diagnosis of a psychotic disorder, obsessive-compulsive disorder, bipolar disorder, a severe substance use disorder, or an eating disorder (as defined by DSM-5 criteria)
  • People who are unable to lie comfortably in a shallow pool of water
  • People who do not complete a required pre-float safety checklist
  • People who test positive for alcohol on a breathalyzer or test positive for drugs on a urine test
  • People who are unwilling to consent or to complete the main parts of the study
  • People for whom MRI scanning is not safe (confirm with trial site for specific MRI-related restrictions)
  • People with unstable medical conditions
  • People who are pregnant
  • People who the research team determines are unlikely to be able to follow the study procedures
  • People who have had a change in dose or type of a medication that may affect brain function (such as anti-anxiety medications, antipsychotics, antidepressants, benzodiazepines, or mood stabilisers) within the six weeks before enrolling

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Phone: 918-340-4116

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Laureate Institute for Brain Research, Inc.
Registry
ClinicalTrials.gov
Start date
10 June 2026
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Adverse effects; Dropout Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov