Myasthenia Gravis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For people with Myasthenia Gravis (MG):
- Adults aged 18 or older
- People who have been diagnosed with myasthenia gravis based on recognised international standards, meaning they have fluctuating muscle weakness plus at least one confirming test result (such as a positive response to a specific medication test, a nerve stimulation test showing a certain pattern, or a specialised muscle fibre test)
- People whose blood tests have confirmed the presence of a specific antibody called anti-AChR
- People whose MG falls into one of three categories: newly diagnosed with no prior treatment; stable on treatment for at least 12 months; or not responding well to standard treatment for at least 12 months
- People who are willing and able to sign a consent form to take part going forward
- For the records-based part of the study, people for whom stored biological samples are already available and who have previously signed a consent form allowing their use
For healthy comparison participants:
- Adults aged 18 or older with no neuromuscular or autoimmune conditions, not currently on immune-affecting medications, and whose blood tests are negative for MG-related antibodies, matched by age and sex to the MG group
Who may not be able to join:
- People whose MG is not linked to the anti-AChR antibody, including those with anti-MuSK antibodies or other non-AChR antibodies
- People whose MG affects only the eye muscles (purely ocular myasthenia gravis)
- People who have another neuromuscular condition alongside MG, such as Lambert-Eaton syndrome, polymyositis, or muscular dystrophies
- People who are pregnant or breastfeeding
- People who are not able to provide informed consent
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 02 5503 3802
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Antibody-induced change in neuromuscular junction electrophysiological activity in a patient serum-derived organoid assay
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.