Phase 2 Endometriosis Trial, Recruiting NCT07728695 Sponsor: Staci Gruber, Ph.D. Condition: Endometriosis
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Phase 2 Endometriosis Trial, Recruiting

NCT07728695
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing and able to give informed consent to participate
  • People who were assigned female sex at birth
  • People who are capable of having menstrual cycles
  • People aged 21 or older
  • People who have been diagnosed with at least one of the following conditions: endometriosis, adenomyosis, or chronic pelvic inflammatory disease (PID)
  • People whose medications and/or mental health therapy have remained unchanged for at least 3 months before the study begins, including any hormonal contraceptives

For a smaller sub-group within the trial (called the PK subgroup), there is one additional requirement:

  • People who are willing to have a small tube (catheter) placed in a vein so that blood samples can be collected at several points during the study

Who may not be able to join:

  • People who currently have a diagnosis of a substance use disorder, a psychotic disorder, bipolar disorder, or an eating disorder (as defined by the DSM-5 medical guidelines)
  • People who are currently using any cannabis or cannabinoid-based products
  • People who have a positive pregnancy test, are currently trying to become pregnant, or are breastfeeding
  • People who have a serious or unstable health condition, such as liver or kidney disease, heart disease, a neurological condition, or who take medications that affect how the body absorbs drugs or empties the stomach (such as GLP-1 medications like semaglutide)
  • People who have nerve-related (neuropathic) pain or pain caused by cancer
  • People who have a known genetic variation that affects how their body processes certain medications through a liver enzyme called CYP2C9 (confirm with trial site)
  • People whose liver function blood test results are more than three times higher than the normal upper limit at the first study visit

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 617-855-2762

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Staci Gruber, Ph.D.
Registry
ClinicalTrials.gov
Start date
1 September 2026
Est. completion
1 January 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Quantification of parent CBD and its primary metabolites, 7-COOH-CBD and 7-OH-CBD, as well as metabolite-to-parent drug exposure ratios (MPR); Inflammatory markers; Circulating anandamide (AEA)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov