Phase 1 study for people with Essential Thrombocythaemia
Recruiting Phase 1
This trial at a glance
Where this trial is running
| Site | City | State or country | Status at this site |
|---|---|---|---|
| Site AU08 | Liverpool | NSW | Not yet recruiting |
| Site AU09 | Sydney | NSW | Recruiting |
| Site AU06 | Melbourne | VIC | Not yet recruiting |
| Site AU03 | Melbourne | VIC | Not yet recruiting |
voxsanity.com.au · trial sites from public registries · registry record synced 14 October 2026 · not medical advice
Who can join
The official eligibility criteria
Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.
Inclusion Criteria:
* Signed informed consent, which includes compliance with the requirements and restrictions listed in the ICF and the protocol.
* Diagnosis/confirmation of ET or MF as defined in the protocol.
* Documented CALR exon-9 mutation.
* Willingness to undergo bone marrow biopsy and aspiration per the Schedule of Assessments.
Exclusion Criteria:
* Presence of any malignancy unless participant has been disease free for at least 2 years.
* History of major bleeding or thrombosis within the last 3 months prior to study enrollment.
* Prior hematopoietic stem cell transplantation or donor leukocyte infusion, or such transplantation or infusion is planned.
* Participants with laboratory values exceeding protocol defined thresholds.
* History of clinically significant or uncontrolled cardiac disease.
* Active HBV, HCV or HIV.
* Known hypersensitivity to DMR-001 or ruxolitinib or any of their components.
Other protocol defined Inclusion/Exclusion Criteria may apply.
Dates on the record
Results, publications and the official record
- No results are posted on the official record yet.
- No publications are listed on the official record yet.
- Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.
Sources and dates
- ClinicalTrials.gov – the record this page reformats
- ClinicalTrials.gov processing date: 7 October 2026.
- This page last checked by Voxsanity: 14 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Letter for your doctor
A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.