Crohn's Disease and Colitis Trial, Recruiting NCT00001184 Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Condition: Crohn's Disease and Colitis
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Crohn's Disease and Colitis Trial, Recruiting

NCT00001184
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Crohn's disease, ulcerative colitis, or a related inflammatory bowel disease (IBD), confirmed by medical tests, scans, or tissue samples
  • You have symptoms that suggest an unclassified inflammatory bowel disease, with lab evidence of intestinal inflammation
  • You have symptoms that could suggest IBD — such as stomach pain, diarrhea, bleeding from the gut, weight loss, fistulae, skin problems, joint pain, eye inflammation, fatigue, or fever — even if no firm diagnosis has been made yet
  • You have a known genetic condition that is linked to a higher risk of IBD, with or without symptoms
  • You are between 0 and 75 years old (those visiting the NIH clinic in person must be over 18 unless samples are being sent in by mail, in which case younger children may be included — confirm with trial site)
  • If you are taking part in a biopsy procedure, your recent blood test results must show healthy enough levels of red blood cells, platelets, and clotting factors (within the last two weeks — confirm specific values with trial site)
  • You are able to give your own consent to take part in the study

Healthy volunteers may also be eligible if:

  • You are willing to give a blood sample and/or have an endoscopy with biopsy for research purposes
  • You are 18 years old or older
  • You are willing to have your samples stored for research

Who may not be able to join:

  • You do not meet the eligibility requirements listed above
  • You have a medical, psychiatric, or personal situation that the research team believes would make it unsafe or unsuitable for you to take part
  • (For healthy volunteers only) You have a history of inflammatory bowel disease
  • (For healthy volunteers only) You currently have an infection in your gut or body that requires antibiotic treatment
  • (For healthy volunteers only) You have any condition that the research team believes puts you at unnecessary risk by joining the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ivan J Fuss, M.D., National Institute of Allergy and Infectious Diseases (NIAID)

Phone: (240) 627-3078

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
7 August 1998

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To identify the molecular abnormalities that result in inflammatory bowel diseases and develop novel therapies based on these discoveries.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov