COPD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
As a patient:
- People aged 2 years or older who have no active infections may be seen in person at the clinic; however, samples sent in for diagnostic purposes may be accepted at any age.
- People who have signs of immune system problems, such as frequent or unusual infections, recurring or long-lasting inflammation, or past test results showing the immune system is not working normally.
- People who have their own doctor outside of the NIH.
As a relative of a patient:
- Biological family members — including a parent, sibling, child, grandparent, aunt, uncle, or first cousin — of an enrolled patient.
- Siblings, children, first cousins, aunts, and uncles must be at least 2 years old and have no active infections to be seen in person at the clinic; however, sent-in samples may be accepted at any age.
- People willing to have their blood stored for future research purposes.
As a healthy volunteer:
- Healthy adults of any sex, aged between 18 and 85 years old.
- People whose haemoglobin level is 11 or above.
- People weighing more than 110 pounds (approximately 50 kg).
- People with no history of injecting drugs intravenously.
- People with no history of activities considered high-risk for exposure to HIV.
- People willing to have blood samples stored for future research and used to create a type of research cell (called iPS cells).
Who may not be able to join:
Patients and relatives of patients:
- People whose immune system problems are caused solely by HIV, cancer treatment drugs, or an underlying cancer may potentially be excluded, as these conditions could interfere with the study's ability to assess immune function (confirm with trial site).
- Pregnant people will not be able to take part in any procedures that could be harmful to the pregnancy or the developing baby.
Healthy volunteers:
- People who have HIV, active hepatitis B or C, or a history of hepatitis B or C since age 11.
- People currently receiving cancer treatment drugs, or who have an underlying cancer.
- People who are pregnant.
- People with a history of heart, lung, or kidney disease, or bleeding disorders.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Harry L Malech, M.D., National Institute of Allergy and Infectious Diseases (NIAID)
Phone: (301) 335-1744
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To establish the pattern and pace of change of disease (frequency, distribution, type and extent of infections, inflammatory lesions and abnormalities of immune function) during a period of up to one year baseline assessment.; To establish the extent of organ involvement (infection and/or inflammation) and organ damage or dysfunction resulting from the abnormality of immune function.; To determine genetic linkage and biochemical correlates of the patient s abnormality of immunity by study of first and second-degree related family members blood cells (buccal smears instead of blood for genetic...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.