Phase 3 Ovarian Cancer Trial, Completed

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with advanced or relapsed ovarian cancer, primary peritoneal cancer, or fallopian tube cancer that has been confirmed by a tissue sample (biopsy).
• You are generally well enough to carry out everyday activities with little or no limitation (confirm with trial site for exact fitness level required).
• You received your first cancer treatment with a platinum-based chemotherapy, and your cancer did not get worse for at least 6 months after finishing it.
• You received a second round of platinum-based chemotherapy, and your cancer responded but then came back.
• Scans have shown your cancer has grown or spread after that second treatment (special timing rules apply if your second treatment included a drug called pegylated liposomal doxorubicin — confirm with trial site).
• Your cancer can be measured on scans at the start of the study.
• Your BRCA gene mutation status (a specific genetic test result) is known, or you are willing to have a blood test to find out before joining.
• Your recent blood test results are within acceptable ranges set by the study.
• Your heart is pumping normally, as shown by a special heart scan.
• Any side effects from your previous treatment (except hair loss) have mostly settled down before you join.
• You have a negative pregnancy test at the start of the study.
• You agree to use effective contraception as required by the study.

Who may not be able to join:

• Your ovarian cancer has been identified as a specific type called "mucinous" ovarian cancer.
• You have had more than 2 previous courses of cancer treatment (note: maintenance therapies and hormonal therapies do not count toward this total — confirm with trial site).
• You have previously been treated with doxorubicin or similar drugs (called anthracyclines) at a total dose above a certain level (confirm with trial site for exact details).
• You are currently pregnant or breastfeeding.
• You have received radiation therapy, chemotherapy, experimental therapy, hormonal therapy, or biological therapy within the 3 weeks before starting this study, or you are currently taking part in another clinical trial.
• You have had another type of cancer in the past, unless it was a minor skin cancer or early-stage cervical cancer that was fully treated, or unless you have been in remission for 5 or more years.
• You have a known allergy or bad reaction to the study drugs (Doxil or dexamethasone) or their ingredients.
• Your cancer has spread to your brain or central nervous system.
• You have significant long-term liver disease, such as cirrhosis or active hepatitis requiring antiviral treatment.
• You have had a heart attack in the last 6 months, moderate-to-severe heart failure, uncontrolled chest pain, serious heart rhythm problems, or other significant heart conditions.
• You have certain ongoing medical conditions, including uncontrolled diabetes, a psychiatric condition that would make it hard to follow the study rules, uncontrolled seizures, a newly diagnosed blood clot in a vein, or an active serious infection.
• Your doctor feels that any other health condition could put you at risk or prevent you from safely taking part in the study.

Important: Always verify eligibility with the trial site directly before applying.