Study for people with Ovarian Cancer

Recruiting Not a phased study

Sources: ClinicalTrials.gov Checked: 11 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Not a phased study
Sponsor University Medical Center Nijmegen
Registry number NCT04294927
Started 1 March 2020 Today 16 October 2026 Estimated completion 17 February 2040

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Chris O'Brien Lifehouse Sydney NSW Recruiting
Westmead hospital Sydney NSW Recruiting
St Andrew War Memorial Hospital Brisbane QLD Recruiting
Royal Brisbane Hospital Brisbane QLD Recruiting
Greenslopes Private Hospital Brisbane QLD Recruiting
Royal Adelaide Hospital Adelaide SA Recruiting
Frances Perry House Melbourne VIC Recruiting
Mercy Hospital Melbourne VIC Recruiting
Epworth Hospital Richmon VIC Recruiting
Western Health St Albans VIC Recruiting
King Edward Memorial Hospital Perth WA Recruiting
The Mater Hospital Brisbane Australia Recruiting
Monash Health Melbourne Australia Recruiting
Peter MacCallum Centre Melbourne Australia Recruiting
Royal Womens Hospital Melbourne Australia Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice

Who can join

Age 25 Years to 50 Years
Sex Female participants only
Healthy volunteers Not accepted
Enrolment target 3000

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

* Women with a class 5 (definitely pathogenic) BRCA1, BRCA2, RAD51C, RAD51D or BRIP1 germline mutation in one of the participating centers.

* Age at inclusion;

* BRCA1: 25-40 years

* BRCA2: 25-45 years

* RAD51C, RAD51D, BRIP1: 25-50 years

* Childbearing completed

* Presence of at least one fallopian tube

* Participants may have a personal history of non-ovarian malignancy

* Informed consent must be obtained and documented according to national and local regulatory requirements and the local rules followed in the institution.

Exclusion Criteria:

* Postmenopausal status (natural menopause or due to treatment)

* Wish for second stage RRO within two years after RRS

* Legally incapable

* Prior bilateral salpingectomy

* A personal history of ovarian, fallopian tube or peritoneal cancer

* Current diagnosis or treatment for malignant disease

Dates on the record

Started 1 March 2020
Estimated completion 17 February 2040
Registry last updated 6 April 2026
Checked by Voxsanity 11 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 6 April 2026.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.