Pulmonary Hypertension Trial, Recruiting NCT01884051 Sponsor: Vanderbilt University Medical Center Condition: Pulmonary Hypertension
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Pulmonary Hypertension Trial, Recruiting

NCT01884051
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Project 1 (includes a skin biopsy component):

  • People diagnosed with a type of high blood pressure affecting the lungs (either idiopathic, heritable, or associated with another condition), or family members of someone with one of these diagnoses
  • People aged 0 to 90 years old (for the skin biopsy part, people aged 12 to 90 years old)

Project 2 (includes blood collection and other testing):

  • People diagnosed with a type of high blood pressure affecting the lungs (either idiopathic, heritable, or associated with another condition), or family members of someone with one of these diagnoses
  • People aged 0 to 90 years old
  • People who can reasonably travel to the clinic for blood collection and other tests
  • People who are able to go without food for a period of time before sample collection and a blood vessel function test

Project 3:

  • People diagnosed with a type of high blood pressure affecting the lungs (either idiopathic, heritable, or associated with another condition), or family members of someone with one of these diagnoses
  • People aged 7 to 90 years old

Who may not be able to join:

Project 1:

  • People with a different diagnosis not listed above
  • People older than 90 years old (or, for the skin biopsy part, people younger than 12 or older than 90)

Project 2:

  • People with a different diagnosis not listed above
  • People who have significant difficulty travelling to the clinic for blood collection and other tests
  • People who are unable to go without food before sample collection and testing

Project 3:

  • People with a different diagnosis not listed above
  • People younger than 7 or older than 90 years old

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: James E Loyd, MD, Vanderbilt University Medical Center

Phone: 800-288-0378

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 September 2012
Est. completion
1 July 2032

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Ratio of sex hormone metabolites; Evaluation of insulin resistance in pulmonary arterial hypertension patients/Clinical trial of Metformin in Pulmonary Arterial Hypertension; Mechanism, safety, and efficacy of ACE-2 (Angiotensin Converting Enzyme 2) in the treatment of PAH.; Clinical Trial of Metformin in Pulmonary Arterial Hypertension

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov