Phase 3 Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have had a radical prostatectomy (surgical removal of the prostate) for confirmed prostate cancer
• People whose cancer was confirmed by a pathologist to be at stage T1, T2, or T3 (meaning the cancer was contained or had only limited spread beyond the prostate)
• People with no signs that the cancer has spread to the lymph nodes or other parts of the body
• People considered low risk for cancer spread to the lymph nodes, with a Gleason score of 6 or 7 (a measure of how aggressive the cancer appears), stage T2 disease, and a PSA level below 20 at the time of diagnosis
• People with a general health and activity level rated as ECOG 0–2 (meaning fully active to capable of basic self-care)
• People with healthy enough kidney function, liver function, and blood cell levels, as measured by specific lab tests (confirm with trial site for exact values)
• People aged 30 to 80 years old at the time of diagnosis, with a life expectancy of at least 3 years
• People whose surgical margins show only a small, limited area of cancer cells at the edge (focally positive margins)
• People who are not planning to receive hormone therapy or radiation therapy after surgery
• People whose PSA level is undetectable at the time of enrolling in the trial

Who may not be able to join:

• People who are more than 3 months past their surgery at the time of enrolling
• People whose cancer was confirmed as stage T3b, T4, or has spread to the lymph nodes
• People who had visible cancer remaining in the body after surgery
• People who received hormone therapy before their surgery
• People with a history of gallbladder problems, gallstones, or a blockage in the bile duct — unless the gallbladder has already been surgically removed
• People who are receiving radiation therapy as the main treatment after surgery
• People with a blood clotting measure (INR) greater than 1.5
• People with liver enzyme levels (AST/ALT) that are two or more times higher than the normal range
• People taking blood-thinning or anti-clotting medications (note: people taking low-dose aspirin at 81mg may be permitted with close monitoring — confirm with trial site)
• People with a history of stomach or duodenal ulcers, or untreated conditions causing excess stomach acid
• People who are currently taking curcumin supplements and are unwilling to stop, or who plan to take curcumin during the study

Important: Always verify eligibility with the trial site directly before applying.