Phase 2 Lymphoma Trial, Recruiting NCT02259556 Sponsor: Chinese PLA General Hospital Condition: Lymphoma
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Phase 2 Lymphoma Trial, Recruiting

NCT02259556
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with CD30-positive Hodgkin lymphoma or Non-Hodgkin lymphoma whose cancer has come back after a stem cell transplant using their own cells, or whose cancer has not responded to at least two multi-drug treatment plans and/or an anti-CD30 antibody treatment.
  • People newly diagnosed with CD30-positive Hodgkin lymphoma or Non-Hodgkin lymphoma who are unable to receive or complete standard chemotherapy.
  • People with a general health and activity score above 60% on standard medical scales (meaning they are able to carry out most daily activities).
  • People with an expected survival of more than 12 weeks.
  • People whose kidney function is within an acceptable range (creatinine level below 2.5 mg/dl).
  • People whose liver enzyme levels are within an acceptable range (no more than 3 times the normal level for ALT and AST).
  • People whose bilirubin level (a marker of liver function) is below 2.5 mg/dl.
  • People whose blood oxygen level is above 90% while breathing normal room air.
  • People with adequate lung function, with key breathing measurements at or above 50% of the expected level (confirm with trial site).
  • People whose own immune T cells are available and show at least 10% expression of a specific marker used in this treatment, as confirmed by a laboratory test.
  • People, or their legal guardians, who are willing to sign an informed consent form confirming they understand this is a research study and have been told about its possible benefits and risks.

Who may not be able to join:

  • People with an active infection such as hepatitis B or C.
  • People who have received an anti-CD30 antibody-based treatment within the past 6 weeks.
  • People currently using systemic corticosteroids (steroid medicines that affect the whole body).
  • People who are pregnant or breastfeeding.
  • People who have confirmed tumour involvement in the lungs or gastrointestinal tissues (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Weidong Han, Ph.D, Chinese PLA General Hospital

Phone: 86-10-66937463

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Chinese PLA General Hospital
Registry
ClinicalTrials.gov
Start date
1 October 2014
Est. completion
1 October 2018

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Occurrence of related adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov