Phase 2 Eczema Trial, Recruiting NCT02365246 Sponsor: Universitaire Ziekenhuizen KU Leuven Condition: Eczema
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Phase 2 Eczema Trial, Recruiting

NCT02365246
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults over 18 years old who have been diagnosed with severe atopic dermatitis (eczema), based on a specific severity score above 40
  • People whose eczema has been ongoing and stable for more than one year
  • People who have previously tried light therapy or one or more immune-suppressing medications (such as cyclosporin A, methotrexate, azathioprine, mycophenolate, or oral steroids), and where that treatment either did not work well enough, caused unacceptable side effects, or could not be used for medical reasons
  • People who are not pregnant and do not plan to become pregnant during the treatment period
  • People who have signed a consent form agreeing to take part in the trial

Who may not be able to join:

  • People who have mild or moderate eczema, rather than severe eczema
  • People whose severe eczema is being managed well with standard treatments, and who can tolerate those treatments without problems
  • People who are pregnant, or who plan to become pregnant during or immediately after the treatment period
  • People with a known allergy to any materials used in the immunoadsorption procedure (a blood-filtering treatment used in this trial)
  • People with serious heart or blood vessel disease
  • People who experience severe bleeding when taking blood-thinning medication
  • People who are currently taking a type of blood pressure medication known as ACE inhibitors
  • People under 18 years of age
  • People who have an active cancer that is not currently in remission
  • People who have not signed the informed consent form

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Marie-Anne Morren, MD, UZ Leuven

Phone: 0032/16337009

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 August 2014
Est. completion
1 December 2025

Where this trial is recruiting

🇧🇪 Belgium

Primary endpoints

clinical improvement (The improvement of Atopic dermatitis will be evaluated with different scales including SCORAD, EASI, LIS, DLQI)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov