Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing and able to sign the official consent form approved by the relevant authorities.
• People who are already enrolled in the ALFA project (Study 45-65 FPM/2012).
• People whose brain MRI scan does not show any findings that would otherwise rule them out of the trial.
• People whose memory and thinking abilities fall within the normal range, based on two standard tests (a general thinking test scoring 26 or above, and a word-finding test scoring 12 or above for naming animals).
• People who score 0 on a standard dementia rating scale, meaning no signs of dementia have been detected.
• People who have a good understanding of the language used in the study and are able to read and write.
• Female participants who have gone through menopause, or who have a negative pregnancy test at the time of the brain imaging scan.

Who may not be able to join:

• People who already have a diagnosed problem with memory or thinking (cognitive impairment).
• People who have been diagnosed with certain mental health conditions, including major depression, generalised anxiety disorder, schizophrenia, or bipolar disorder.
• People who have significant vision or hearing difficulties.
• People with a history of brain infection (encephalitis), stroke, or seizures (not including childhood febrile convulsions caused by fever).
• People whose MRI scan shows serious blood vessel disease in the brain (such as multiple strokes) or a brain tumour.
• People for whom an MRI scan is not safe or possible — for example, due to metal implants in the body — or who have a strong fear of enclosed spaces that would prevent them from completing the scan, as assessed by the doctor at the trial site.
• People who have taken part in another clinical trial involving an experimental medication within the 30 days before screening, or who have received a radioactive substance within a specific timeframe before this study's imaging procedure (confirm with trial site for exact timing details).

Important: Always verify eligibility with the trial site directly before applying.