Ovarian Cancer Trial, Recruiting NCT02732860 Sponsor: University Health Network, Toronto Condition: Ovarian Cancer
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Ovarian Cancer Trial, Recruiting

NCT02732860
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

"Who might be able to join this trial:

  • People who are older than 18 years of age.
  • People who have a confirmed diagnosis of Triple Negative Breast Cancer that is either at an advanced (spread) stage and has not yet been treated with systemic (whole-body) therapy, or at an earlier stage with remaining tumour detected after completing chemotherapy containing specific drug types (anthracyclines and taxanes).
  • People who have confirmed advanced colorectal (bowel) cancer that has spread, treated with no more than one round of systemic (whole-body) therapy, and who are either having surgery to remove liver tumours or have tumours that a doctor can safely biopsy.
  • People who have confirmed advanced high-grade serious ovarian cancer that has either returned (with a life expectancy of at least 12 months), or is at Stage III or IV with remaining disease after chemotherapy, or is considered at high risk of returning.
  • People who have a confirmed solid tumour that does not fall into the above categories, where the trial team has determined there is a particular reason to investigate new treatments (confirm with trial site).
  • People whose cancer can be safely accessed for a tissue sample through biopsy or surgery.
  • People who are in generally good physical condition, able to carry out normal daily activities or light work (this is measured using a standard scale called ECOG, scores 0–1).
  • People who are willing and able to give their own signed consent to participate.

Who may not be able to join:

  • People with serious problems affecting the liver, kidneys, heart, or other major organs that are likely to limit safe participation in clinical trials.
  • People who have cancer that has spread to the brain.
  • People who have a condition that affects their ability to understand and agree to participation, such as dementia or severe cognitive impairment.
  • People for whom having a biopsy procedure would not be medically safe or suitable.

Important: Always verify eligibility with the trial site directly before applying."

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David Cescon, MD, Princess Margaret Cancer Centre

Phone: 416-946-2245

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 December 2015
Est. completion
4 January 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Measure of drug sensitive pPDX to a panel of drugs as a predictor of clinical response in matched host; Rate of results reporting; Rate of pPDX engraftment

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov