Phase 1 Pulmonary Hypertension Trial, Recruiting NCT02966665 Sponsor: Russell Richardson Condition: Pulmonary Hypertension
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Phase 1 Pulmonary Hypertension Trial, Recruiting

NCT02966665
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Healthy adults between 18 and 30 years old with no health conditions that would affect their participation
  • Healthy adults aged 65 or older with no health conditions that would affect their participation
  • People who are already scheduled to have a routine coronary angiography (a procedure to look at the heart's blood vessels)
  • People who have been diagnosed with mild to moderate COPD (a lung condition that makes breathing difficult)
  • People who have a specific type of high blood pressure affecting the lungs, known as idiopathic or heritable Group 1 pulmonary arterial hypertension
  • People with Class I, II, or III heart failure symptoms as classified by the New York Heart Association (a standard medical rating system for heart failure severity — confirm with trial site)
  • People who have been diagnosed with ongoing high blood pressure

Who may not be able to join:

  • People with severe COPD, including those who need supplemental oxygen or have very significantly reduced lung function
  • People with a history of heart attack
  • People who have previously had a procedure to unblock heart arteries using a small tube or balloon (percutaneous coronary revascularisation)
  • People who have previously had coronary artery bypass graft surgery (open-heart surgery to reroute blood around blocked arteries)
  • People currently experiencing unstable chest pain (unstable angina)
  • People with a history of a specific type of chest pain caused by artery spasms (variant angina)
  • People whose heart pumps less than 50% of blood out with each beat (ejection fraction below 50%)
  • People with significant kidney disease, based on a specific measure of kidney filtering ability falling below a certain level
  • People for whom an MRI scan would be unsafe — for example, those with a pacemaker, certain metal implants, or certain types of heart valves
  • People who are pregnant
  • People with physical health conditions (other than COPD, pulmonary arterial hypertension, heart failure, or high blood pressure) that the trial investigator determines would prevent safe participation

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Russell Richardson, Ph.D., George E Wahlen VA Medical Center

Phone: 801-584-2522

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Russell Richardson
Registry
ClinicalTrials.gov
Start date
1 September 2008
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Limb Blood Flow

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov