COPD Trial, Recruiting NCT03033251 Sponsor: Unity Health Toronto Condition: COPD
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COPD Trial, Recruiting

NCT03033251
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a flare-up of COPD (chronic obstructive pulmonary disease) causing a buildup of carbon dioxide in the blood, shown by specific blood gas test results (confirm with trial site)
  • People whose breathing rate is 20 breaths per minute or more during the flare-up
  • People who are visibly using the muscles in their neck, shoulders, or chest to help them breathe
  • People who have already started using a breathing support mask (NIV) or high-flow oxygen through the nose (HFNC) since being admitted to hospital
  • People who speak English
  • Adults aged over 40 years

Who may not be able to join:

  • People whose blood acidity level is severely abnormal (below a pH of 7.25), indicating very serious breathing failure
  • People whose level of consciousness or alertness is significantly reduced
  • People who need an emergency breathing tube (intubation) right away
  • People who have a collapsed lung with a chest drain and an ongoing air leak
  • People whose blood pressure or circulation is dangerously unstable and requires medication to maintain it
  • People who are unable or unwilling to cooperate with the trial procedures
  • People who have injuries to the skin, chest wall, or abdomen that could be made worse by placing a sensor on the body's surface
  • People where the treating doctor, based on their clinical judgement, does not consider participation appropriate
  • People with a body mass index (a measure of weight relative to height) above 40

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +1 416 864 5686

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Unity Health Toronto
Registry
ClinicalTrials.gov
Start date
2 September 2018
Est. completion
11 April 2025

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Change in work of breathing between NIV and HFNC

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov