Phase 2 Lymphoma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with Non-Hodgkin's Lymphoma (NHL) where the cancer has responded to chemotherapy, with eligibility depending on the specific type of NHL and how many treatment rounds have been completed (confirm with trial site for details on specific sub-types)
• People who have been diagnosed with Hodgkin Lymphoma (HL) whose cancer has not been fully controlled by previous treatments, and whose disease has shown at least some response to chemotherapy
• People with certain types of lymphoma who have high-risk features at diagnosis, such as advanced-stage disease or high levels of certain markers in the blood (confirm with trial site for full list of high-risk features)
• People who are HIV-positive may still be considered, provided they have been assessed by an HIV/infectious disease specialist before joining, are on the most effective available HIV treatment, have a CD4+ cell count of at least 50 per microlitre, and have had a low HIV viral load (no more than 100,000 copies per mL) confirmed on two separate tests taken four weeks apart, with the most recent test within 30 days of enrolment
• People with a performance status score of 80% or above on standard scales used for adults (aged 16 and over) or children (under 16), though a lower score may be accepted if poor health is caused by the lymphoma itself (confirm with trial site)
• People whose blood counts, kidney function, liver function, heart function, and lung function all meet certain minimum levels as assessed by the treating team
• People with a history of lymphoma involvement in the brain or spinal cord may be eligible for a specific treatment arm, provided they have completed standard treatment for this and show no signs of the disease progressing at the time of enrolment
• People who are carriers of Hepatitis B (but not actively ill from it)
• People who are at least four weeks past their last chemotherapy treatment (or six weeks if the treatment included a specific class of drugs called nitrosoureas)
• People who are able and willing to use effective contraception for the duration of treatment, if there is any possibility of pregnancy
• People who are able to give voluntary written consent to participate

Who may not be able to join:

• People who are currently pregnant or breastfeeding — a blood or urine pregnancy test is required within 14 days before registration for anyone who could potentially become pregnant
• People whose lymphoma has not responded to chemotherapy (chemotherapy-resistant disease)
• People who are eligible for another transplant trial that has been given a higher priority
• People who have an active, unrelated infection at the time of enrolment

Important: Always verify eligibility with the trial site directly before applying.