Phase 2 Ovarian Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have ovarian, fallopian tube, or peritoneal cancer that has come back or not gone away, and this was found within 6 months of finishing your most recent chemotherapy that contained platinum.
• Your cancer is one of these specific types: serous, endometrioid, mucinous, undifferentiated, clear cell, mixed epithelial, transitional cell, malignant Brenner's tumor, or adenocarcinoma (confirm with trial site if unsure of your type).
• You have had one prior chemotherapy treatment for your original diagnosis that included a platinum-based drug (such as carboplatin or cisplatin).
• You have had no more than two chemotherapy treatments in total for cancer that came back or did not go away.
• You may have had one additional non-chemotherapy treatment (such as hormones, monoclonal antibodies, or targeted therapy) for recurring or persistent disease.
• If you are able to become pregnant, you must have a negative pregnancy test before joining and must be using an effective form of contraception.
• Your bone marrow, kidneys, liver, and nervous system are all functioning well enough (as measured by blood tests — confirm with trial site).
• You have recovered from any recent surgery, radiation, or chemotherapy, with only mild or no lasting side effects.
• You do not currently have an active infection requiring antibiotics (a simple urinary tract infection is generally acceptable).
• Any hormone therapy aimed at your cancer must have been stopped at least one week before joining.

Who may not be able to join:

• Your cancer did not respond to platinum-based chemotherapy at all (known as platinum-refractory disease).
• You have been diagnosed with another cancer within the past 5 years (except for certain treated skin cancers).
• You are currently receiving chemotherapy or radiation therapy, or you have received any cancer-directed treatment — including biological or immune therapies — within the last three weeks.
• You have previously been treated with a type of drug called a kinase inhibitor (confirm with trial site if unsure).
• You have a history of certain serious gut problems, including fistula, significant bleeding, perforation, or peptic ulcer disease.
• You are currently pregnant or breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.