Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Healthy younger adults (ages 18–49):
- People aged 18 to 49 years old.
- People who are willing and able to give informed consent to participate.
- People whose muscles in the upper arm or hand respond to a type of brain stimulation called TMS, as checked during a screening session.
Healthy older adults (ages 50 and over):
- People aged 50 years or older.
- People who are willing and able to give informed consent to participate.
- People whose muscles in the upper arm or hand respond to TMS stimulation, as checked during a screening session.
Stroke patients:
- People aged 18 or older who have had a stroke.
- People who have weakness in one or both arms but can still voluntarily move a finger, hand, wrist, or elbow in the affected arm.
- People whose stroke happened more than 6 months before joining the trial.
- People whose brain still responds to TMS stimulation in the affected arm, as checked during a screening session.
- People who are willing and able to give informed consent (if there is any doubt about a person's ability to consent, a specialist protection unit at the NIH will assess this).
Who may not be able to join:
Healthy younger and older adults:
- People who have a serious neurological or medical condition, such as Parkinson's disease or multiple sclerosis.
- People who have a history of seizures.
- People who regularly take antipsychotic medications (such as chlorpromazine or clozapine), tricyclic or other antidepressants, benzodiazepines, or prescription stimulants.
- People who have a pacemaker, implanted pump, implanted stimulator, cochlear implant, or metal objects inside the eye or skull.
- People who have been diagnosed with severe hearing loss.
- People who are currently pregnant.
- People who are staff members of the research section running this trial.
Stroke patients:
- People who have a serious neurological or medical condition in addition to their stroke, such as Parkinson's disease or multiple sclerosis.
- People who have had a brainstem stroke.
- People who have a history of seizures.
- People who regularly take antipsychotic medications (such as chlorpromazine or clozapine), benzodiazepines, or prescription stimulants.
- People who have a pacemaker, implanted pump, implanted stimulator, cochlear implant, or metal objects inside the eye or skull.
- People who have been diagnosed with severe hearing loss.
- People who are currently pregnant.
- People who are staff members of the research section running this trial.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Leonardo G Cohen, M.D., National Institute of Neurological Disorders and Stroke (NINDS)
Phone: (301) 451-1335
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
We will study if corticospinal excitability varies across different sensorimotor alpha EEG waveform oscillation phases in healthy older adults and chronic stroke patients with weakness in one or both arms.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.