Prostate Cancer Trial, Recruiting NCT03327675 Sponsor: Universitaire Ziekenhuizen KU Leuven Condition: Prostate Cancer
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Prostate Cancer Trial, Recruiting

NCT03327675
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Group 1 (patients planning surgery):

  • You are under 75 years old and have been diagnosed with prostate cancer confirmed by a tissue biopsy (specifically a type called invasive adenocarcinoma)
  • Your cancer is considered intermediate to high risk, with at least a 5% chance of the cancer having spread to nearby lymph nodes, based on a specific medical calculation tool (the Briganti nomogram)
  • You are scheduled to have your prostate surgically removed, along with an extended removal of nearby lymph nodes

Group 2 (patients whose cancer has returned after treatment):

  • You have been diagnosed with prostate cancer confirmed by a tissue biopsy
  • Your PSA blood test level has risen to 0.2 ng/ml or above on two separate tests after having had a main prostate treatment (such as surgery or radiotherapy)
  • You are generally well enough to carry out light activity and care for yourself (confirm with trial site)
  • You are over 18 years old

Who may not be able to join:

Group 1:

  • Your scans (MRI) have already shown that cancer has spread to lymph nodes in the pelvis
  • Your bone scan shows the cancer has spread to the bones (if your PSA level is above 20 ng/ml)
  • Your general health and ability to carry out daily activities is significantly limited (confirm with trial site)
  • You have previously had radiotherapy to the pelvic area or prostate removal surgery
  • You have had another type of cancer in the last 5 years, other than a successfully treated common skin cancer (basal cell carcinoma)
  • There are personal, family, social, or location-related reasons that might make it difficult for you to follow the trial's schedule and requirements (confirm with trial site)

Group 2:

  • Your testosterone level in your blood is below 50 ng/ml
  • You have cancer spread (metastases) that is causing symptoms
  • Your MRI scan shows the cancer has come back in the area where the prostate was
  • Your PSA level has been rising while you are already on hormone-related treatments for prostate cancer (confirm with trial site for specific treatments)
  • You have previously had chemotherapy for prostate cancer
  • You have taken certain medications in the past month that are known to affect PSA levels, such as fluconazole, finasteride, or steroids (confirm with trial site)
  • You have a condition that prevents you from understanding the trial information or giving your agreement to take part

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Karolien Goffin, MD, PhD, UZ Leuven

Phone: 003216343714

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
22 September 2017
Est. completion
1 December 2025

Where this trial is recruiting

🇧🇪 Belgium

Primary endpoints

68Ga-PSMA PET/MR imaging accuracy before radical prostatectomy + pelvic lymph node dissection [RP + PLND]. Work unit 1. 68Ga-PSMA PET/MR imaging accuracy in patients with biochemical recurrence after primary treatment. Work unit 2.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov