Phase 2 COPD Trial, Recruiting NCT03331302 Sponsor: University of Virginia Condition: COPD
Back to Copd

Phase 2 COPD Trial, Recruiting

NCT03331302
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must have been diagnosed with COPD (a lung condition that makes it hard to breathe).
  • You must be at your usual, stable level of health on the day of the scan — not in the middle of a flare-up or worsening of symptoms.
  • You must be classified into a COPD category according to a standard medical grading system called GOLD (confirm with trial site).
  • You must be a current or former smoker.
  • You must have a smoking history of at least 10 "pack years" — for example, smoking one pack a day for 10 years, or two packs a day for 5 years.

Who may not be able to join:

  • People who have been diagnosed with asthma.
  • People who need to use oxygen at home all the time.
  • People whose blood oxygen level is below 92% on the day of the scan, as measured by a finger clip device.
  • People whose lung function (a breathing test result called FEV1) is below 25% of what is considered normal.
  • People who are pregnant or breastfeeding.
  • People who have claustrophobia (fear of enclosed spaces), or certain metal devices in their body such as a pacemaker, inner ear implants, aneurysm clips, or metal fragments in the eye, as these are not safe in an MRI scanner.
  • People who have any implanted device that cannot be confirmed as safe for use in an MRI scanner.
  • People whose chest is larger than approximately 42 inches around, as they may not fit the scanning equipment used in this study.
  • People with a history of a heart condition present from birth, long-term kidney failure, or severe liver scarring (cirrhosis).
  • People who are unable to follow simple instructions or remain still for around 10 seconds.
  • People who have had a chest or respiratory infection in the 2 weeks before the scan.
  • People with a history of heart attack, stroke, or poorly controlled high blood pressure.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Yun M Shim, MD, University of Virginia

Phone: 4342436074

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 September 2018
Est. completion
30 June 2020

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Ventilation imaging resolution comparison between MRI and scintigraphy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov