Alzheimer's Disease Trial, Recruiting NCT03472664 Sponsor: Wake Forest University Health Sciences Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT03472664
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with amnestic mild cognitive impairment (a type of memory problem that is more than normal ageing but not yet dementia)
  • People who have a family member, friend, or carer who knows them well and can provide information about them to the study team
  • People whose general health has been stable for around 3 months before the screening visit, as assessed by the study doctor
  • People whose medications have been stable for around 4 weeks before the screening visit, as assessed by the study doctor
  • People who are able to complete the initial assessments at the start of the trial

Who may not be able to join:

  • People who have been diagnosed with a brain or nervous system disease other than mild cognitive impairment
  • People who have had a significant stroke
  • People who have, or have had in the past year, a focal brain lesion, a head injury involving loss of consciousness, or a major psychiatric condition such as psychosis, major depression, bipolar disorder, or alcohol or substance misuse
  • People whose vision or hearing difficulties would prevent them from taking part in the study activities
  • People who have diabetes and are currently taking medication to manage it
  • People with significantly elevated liver enzyme levels (confirm with trial site)
  • People with an active cancer diagnosis (stable prostate cancer and certain skin cancers may be acceptable — confirm with trial site)
  • People who have had epilepsy or a seizure within the past year
  • People who are unable to have an MRI scan, for example due to claustrophobia, metal implants in the head or face, or a pacemaker
  • People with serious medical illness or organ problems, such as poorly controlled high blood pressure, heart disease, chronic lung disease, liver disease, or kidney disease

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Suzanne Craft, PhD, Wake Forest University Health Sciences

Phone: (336) 713-8010

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
16 July 2018
Est. completion
1 April 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Cerebrospinal Fluid (CSF) Abeta42

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov