Osteoarthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are beginning rehabilitation for their first-ever acute lateral ankle sprain (mild, moderate, or severe)
- People whose ankle sprain happened within 72 hours before joining the study
- People whose ankle sprain was diagnosed by a doctor, medic, athletic trainer, physical therapist, or another qualified medical provider working in an operational setting
Who may not be able to join:
- People who have a personal or family history of epilepsy or seizures
- People who have a history of migraine headaches
- People who have a foreign object in their eye, increased pressure in the skull, an open head injury, or a significant closed head injury
- People who have cochlear implants (hearing devices surgically placed in the ear)
- People who have implanted brain stimulators, aneurysm clips, or any other metal in the head (not including the mouth)
- People who have implanted medication pumps, pacemakers, or lines placed inside the heart
- People who are currently taking tricyclic antidepressants, antipsychotic medications, or other drugs known to lower the threshold for seizures
- People who have been diagnosed with a major psychiatric disorder
- People who have a history of illicit drug use
- People who currently misuse alcohol or are going through alcohol withdrawal
- People who have a history of heart disease
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Phillip Gribble, PhD, University of Kentucky
Phone: 859-323-9850
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Ankle re-injury rate; Change in mental quality of life; Change in physical quality of life; Change in physical activity; Change in self-reported Functional Ankle Instability; Change in self-reported Ankle Instability; Change in self-reported Ankle Disability; Change in dynamic balance; Change in ankle dorsiflexion Range of Motion; Change in corticomotor Excitability - Active Motor Threshold; Change in corticomotor Excitability - Cortical Silent Period; Change in Spinal Excitability; Change in White Mater Structural Integrity; Change in Ankle cartilage relaxation; Change in Ankle Articular Cart...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.