Alzheimer's Disease Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with Alzheimer's disease with mild or major memory and thinking problems, with a certain level of severity confirmed by a rating scale (confirm with trial site)
• You have been diagnosed with major depression, and your current episode of depression has lasted more than 4 weeks but less than 5 years
• You tried antidepressant medication but it either did not work for you or you could not tolerate it
• You are willing and able to give your consent to participate in the study
• You are able to follow the treatment schedule as required by the trial
• If you take medications, your doses have been stable for at least 2 months and are not expected to change during the study
• You have passed a safety screening questionnaire related to the brain stimulation treatment used in this trial (confirm with trial site)
• You have a family member, friend, or caregiver who can fill out questionnaires about you during the study

Who may not be able to join:

• You have any metal implants in your head, such as ear implants, brain stimulators, or aneurysm clips (metal dental work in the mouth is generally okay — confirm with trial site)
• You have or have had increased pressure in your brain, which may raise the risk of seizures
• You have a cardiac pacemaker
• You have an implanted medication pump inside your body
• You have a central venous line (a tube inserted into a large vein — confirm with trial site)
• You have a significant heart condition or a history of stroke
• Your memory loss is thought to be significantly related to blood vessel problems in the brain (confirm with trial site)
• You have a history of psychosis, bipolar disorder, an eating disorder, OCD, PTSD, or a type of dementia other than Alzheimer's
• You have used alcohol or drugs in a harmful way within the last 6 months
• You have a history of stroke or other damage or abnormalities in your brain
• You have a personal history of epilepsy or seizures
• You have a family history of epilepsy or seizures
• You are currently pregnant or breastfeeding
• You are currently taking certain psychiatric medications, including antidepressants, antipsychotics, or mood stabilisers, due to an increased risk of seizures
• You are currently taking the medication memantine
• You have had an abnormal brain MRI (brain scan) in the past
• You have significant hearing loss that requires you to use hearing aids
• You have an untreated thyroid condition (either underactive or overactive thyroid)

Important: Always verify eligibility with the trial site directly before applying.