Glaucoma Trial, Recruiting NCT03675412 Sponsor: Wills Eye Condition: Glaucoma
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Glaucoma Trial, Recruiting

NCT03675412
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 18 and 90 years old
  • People who have been diagnosed with primary open angle glaucoma (mild, moderate, or advanced stage)
  • People who have healthy eyes with no eye disease

Who may not be able to join:

  • People who have eye or general health conditions that are likely to affect the results of a specific eye scan called OCTA
  • People who have more than a moderate level of cataracts (clouding of the eye lens)
  • People who have uncontrolled eye movement (nystagmus)
  • People who are unable to focus their gaze on a target during eye testing
  • People who have macular degeneration beyond mild early changes
  • People who have diabetic retinopathy (eye damage related to diabetes)
  • People who have a type of glaucoma caused by abnormal blood vessel growth, or other non-glaucoma optic nerve conditions
  • People who currently have swelling at the back of the eye (macular edema), have previously had laser treatment to the retina, or have inflammatory conditions affecting the retina or underlying eye tissue
  • People who have conditions affecting the shape of the cornea (front surface of the eye), such as keratoconus, corneal ectasia, or central corneal scarring
  • People who have rheumatological (joint and immune) diseases or Raynaud's phenomenon (a condition affecting blood flow to the fingers and toes)
  • People who are pregnant or breastfeeding
  • People who have a mental illness or alcohol addiction
  • People who have pre-existing bladder symptoms, heart disease, or a sleep disorder
  • People whose glasses or contact lens prescription is stronger than a certain level (confirm with trial site)
  • People who may have a tolerance to caffeine from drinking more than one cup of coffee per day

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: M. Reza Razeghinejad, MD, Wills Eye Hospital

Phone: 215-928-7023

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Wills Eye
Registry
ClinicalTrials.gov
Start date
30 December 2018
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Blood flow change in back of eye before and after caffeine

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov