Alzheimer's Disease Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people with dementia:

• A doctor has confirmed a diagnosis of probable Alzheimer's disease
• The dementia is mild, based on results from standard memory and thinking tests (confirm with trial site for specific scores)
• The person is older than 55 years
• The person is able to follow the study procedures
• The person has vision of at least 20/400 (with glasses or contacts if needed) in at least one eye
• The person has a legally authorised representative who can sign the consent form and attend the study visit with them

For people without dementia (comparison group):

• The person is older than 55 years
• The person is able to follow the study procedures
• The person is able to hold their gaze steady during the eye-imaging procedure
• The person has vision of at least 20/40 (with glasses or contacts if needed) in at least one eye
• The person has no diagnosis of dementia, based on standard memory and thinking tests (confirm with trial site for specific scores)

Who may not be able to join:

• People who have a neurological condition unrelated to Alzheimer's disease that affects the brain or nervous system, such as multiple sclerosis or Parkinson's disease
• People whose eye examination in the past year showed eye diseases that could affect the study results, such as glaucoma, diabetic eye disease, or high blood pressure-related eye damage
• People who have cloudiness in the eye — such as cataracts, corneal scarring, or cloudiness in the gel inside the eye — that could interfere with retinal imaging
• People who have had previous eye surgery, except for straightforward cataract removal with a standard lens implant
• People who are unable to hold their gaze steady during the eye scan, or who are unable to give informed consent
• People whose prescription glasses strength falls outside a certain range, or who have a significant level of astigmatism (confirm with trial site for specific measurements)
• People who have had diabetes for more than 10 years, or whose recent blood sugar control levels were above a certain threshold in the 180 days before the eye scan
• People with uncontrolled high blood pressure above a certain level (confirm with trial site for specific readings)
• People with an irregular heartbeat, or a heart rate outside the range of 50 to 110 beats per minute
• People who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.