Lymphoma Trial, Recruiting NCT03810196 Sponsor: Children's Hospital of Philadelphia Condition: Lymphoma
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Lymphoma Trial, Recruiting

NCT03810196
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People under 25 years of age
  • People who have not previously had a stem cell transplant from a donor (this would be their first one)
  • People diagnosed with certain blood cancers that carry a high risk of coming back, including acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), myelodysplastic syndromes (MDS), mixed or bi-phenotypic leukemia, lymphoblastic or Burkitt's lymphoma, or juvenile myelomonocytic leukemia (JMML)
  • People whose blood cancer has either returned, shows signs of remaining after treatment, or has features that suggest a higher risk of returning
  • People whose heart, lungs, kidneys, liver, and other organs meet the health standards set by the transplant team, and who meet the infection-related requirements (confirm with trial site)
  • People who have a parent or guardian who can sign the consent form, or who are over 18 and can sign it themselves

Who may not be able to join:

  • People whose disease, organ health, or infection status does not meet the transplant team's required standards
  • People for whom no suitable donor is available to provide stem cells collected from the bloodstream
  • People with certain inherited genetic conditions, including Fanconi anemia, Kostmann syndrome, dyskeratosis congenita, or other conditions affecting the body's ability to repair DNA
  • People with Hodgkin lymphoma, or types of lymphoma that are not Burkitt's or lymphoblastic lymphoma
  • People who are pregnant

Regarding the donor:

  • A suitable unrelated donor must meet the criteria set by the National Marrow Donor Program
  • The donor must have compatible tissue typing (HLA matching) with the patient
  • The donor must be willing to receive a medication to stimulate stem cell production and undergo stem cell collection from the blood

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Timothy Olson, MD, PhD, Children's Hospital of Philadelphia

Phone: 215-590-2820

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Children's Hospital of Philadelphia
Registry
ClinicalTrials.gov
Start date
1 March 2019
Est. completion
1 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of acute graft vs. host disease (GVHD)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov