Phase 2 Prostate Cancer Trial, Recruiting NCT03824652 Sponsor: Stephen Freedland Condition: Prostate Cancer
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Phase 2 Prostate Cancer Trial, Recruiting

NCT03824652
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with prostate cancer (a specific type called adenocarcinoma), confirmed by a laboratory test.
  • People who had a biopsy with at least 10 tissue samples taken, with each sample examined separately to identify exactly where the cancer is located.
  • People whose biopsy results show a cancer grade of Gleason 7 or higher (grade group 2 or above), indicating a moderate to high aggressiveness level.
  • People who are planning to have their prostate surgically removed.
  • People who are willing to follow their usual diet with the possible addition of 2 ounces of walnuts per day.
  • People who can read, write, and understand English.
  • People aged 18 or older.

Who may not be able to join:

  • People who have a nut allergy.
  • People who have previously received hormone therapy or anti-androgen therapy for prostate cancer.
  • People who have used a type of medication called 5-alpha reductase inhibitors in the past 6 months (confirm with trial site for specific drug names).
  • People who have previously had radiation treatment or a freezing treatment directed at the prostate.
  • People who are currently following a modified diet or weight loss program, or who are taking supplements containing omega-3s (such as fish oil).
  • People who currently have another active cancer, with the exception of certain common skin cancers (basal cell or squamous cell carcinoma).
  • People who have significant other health conditions — such as serious heart, lung, or liver disease, alcohol or drug addiction, or conditions affecting how the body absorbs nutrients — that the study doctor considers would make participation unsuitable.
  • People who have psychological or mental health conditions that could affect their ability to give informed consent or follow the study requirements.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Stephen Freedland, MD, Cedars-Sinai Medical Center

Phone: 310-423-0333

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Stephen Freedland
Registry
ClinicalTrials.gov
Start date
22 April 2019
Est. completion
1 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Mean difference in prostatic tissue Ki67 expression from baseline biopsy to RP

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov