Phase 3 Breast Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 75 years old
- People with invasive breast cancer in one breast only, confirmed by a tissue sample (biopsy), at a specific stage (pT1–3)
- People who have had breast-conserving surgery (such as a lumpectomy) or a full breast removal (mastectomy)
- People who have had or are having breast reconstruction surgery
- People whose cancer has spread to nearby lymph nodes under the arm, confirmed by a tissue sample — including those where only the sentinel (first) lymph node was found to be positive, without full lymph node removal
- People expected to live more than 5 years
- People whose surgery removed the cancer with clear edges of at least 2mm around the tumour
- People who are in good general health, as measured by a standard medical scoring system (Karnofsky Performance Status of 80 or above)
- People whose tumour has been tested for certain markers (estrogen receptor, progesterone receptor, HER-2, and Ki67) — these tests can be done on either the breast tumour or the lymph nodes
- People who are able and willing to provide written consent to participate
Who may not be able to join:
- People whose cancer has spread to lymph nodes above the collarbone, to certain lymph nodes near the breastbone on the same side, or where there are remaining lymph nodes under the arm that may need an extra radiation dose (confirm with trial site)
- People who are pregnant or breastfeeding
- People with serious non-cancer medical conditions — for example, severe heart disease, serious heart rhythm problems, or severe lung disease — that would make radiation treatment unsafe
- People diagnosed with another type of cancer (other than a specific type of skin cancer called basal cell carcinoma, or pre-cancerous cells of the cervix) within the 5 years before joining the trial
- People who have cancer in both breasts at the same time, including a non-invasive type called DCIS in the other breast
- People who have previously had radiation therapy to the chest, underarm, or neck area
- People with an active connective tissue disease affecting blood vessels (confirm with trial site)
- People whose cancer has spread to other parts of the body, or whose tumour is classified as T4 (a more advanced local stage)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Jia-Yi Chen, Ruijin Hospital
Phone: +86-021-64370045
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Locoregional recurrence (LRR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.