Alzheimer's Disease Trial, Recruiting NCT03840083 Sponsor: University of Massachusetts, Amherst Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT03840083
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 80 years old
  • People who are considered healthy sleepers
  • People who have not been diagnosed with a sleep disorder or a brain/nerve-related condition

Who may not be able to join:

  • People who have previously been diagnosed with a sleep disorder, or whose sleep monitoring results during a screening night show signs of breathing problems during sleep, frequent leg movements during sleep, difficulty falling asleep, or poor overall sleep quality
  • People who have previously been diagnosed with a neurological illness or have had a head injury
  • People who typically sleep fewer than 5 hours or more than 9 hours per night on average
  • People who currently work shift work, or who cannot maintain a regular sleep schedule in the week before testing
  • People who currently use psychiatric medications, recreational drugs, or medications that affect sleep (including sleep aids, cold medicines taken within the past week, clonidine, or stimulant medications)
  • People who drink more than 4 cups of caffeinated drinks (such as coffee, tea, or cola) per day
  • People who drink more than 10 alcoholic drinks per week
  • People who are pregnant or who gave birth within the last 12 months
  • People with a history of bipolar disorder or mania, or whose depression screening score suggests current depression
  • People who have had unusual sleep patterns in the past 3 months, such as shift work or travel across more than 2 time zones
  • People whose cognitive screening results fall below a certain threshold, suggesting possible cognitive difficulties (confirm with trial site)
  • People whose depression screening score reaches a level indicating depression (confirm with trial site)

For the parts of the trial that involve MRI scanning, additional criteria apply — people may not be able to join if they:

  • Are left-handed or use both hands equally
  • Experience claustrophobia (fear of enclosed spaces)
  • Have any metal in or on their body
  • Are pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Massachusetts, Amherst
Registry
ClinicalTrials.gov
Start date
15 July 2018
Est. completion
14 July 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in memory accuracy for intervention compared to control

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov