Ovarian Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

The trial has five separate groups. People may be considered for one of the following groups:

Group I:

• People with a body mass index (BMI) between 18.5 and 25.0
• People who have a type of ovulation problem classified as "Group 1" by the World Health Organization
• People with low or normal levels of certain reproductive hormones (FSH and LH) and low estrogen levels
• People who do more than 5 hours per week of moderate to vigorous exercise and have low energy intake relative to their body composition
• People who have had other causes of their ovulation problems ruled out
• People who have signed an informed consent form

Group II:

• People diagnosed with Polycystic Ovary Syndrome (PCOS) of a specific type (phenotype I, II, or III by NIH-2012 guidelines) that includes high levels of male hormones
• People with a BMI between 18.5 and 40.0
• People who have signed an informed consent form

Group III:

• People diagnosed with a specific type of PCOS (phenotype IV by NIH-2012 guidelines)
• People with a BMI between 18.5 and 40.0
• People who have signed an informed consent form

Group IV:

• People with a BMI between 18.5 and 25.0
• People who have regular menstrual periods
• People with normal reproductive hormone levels during the first part of their menstrual cycle
• People who do more than 5 hours per week of moderate to vigorous exercise and eat enough to support their body composition
• People who have signed an informed consent form

Group V:

• People with no signs or symptoms of high male hormone levels
• People who do no exercise or only light physical activity
• People who have regular menstrual periods
• People with a BMI between 18.5 and 40.0
• People who have signed an informed consent form

Who may not be able to join:

• People who have taken certain medications in the past 6 months that can affect ovulation, including steroids, antipsychotics, antidepressants, contraceptives, hormones, or opioids
• People who are currently pregnant or breastfeeding, or who have been pregnant or breastfeeding in the past 6 months
• People who have a uterine condition called Asherman's syndrome or other structural problems affecting the reproductive tract
• People who currently smoke or drink more than 40g of alcohol per day
• People who have a previous diagnosis of blood sugar problems, high blood pressure, abnormal cholesterol, heart or lung disease, kidney disease, liver disease, coeliac disease, any condition affecting nutrient absorption, chronic inflammatory disease, or cancer

Important: Always verify eligibility with the trial site directly before applying.