Phase 3 Alzheimer's Disease Trial, Recruiting NCT03848312 Sponsor: University of South Florida Condition: Alzheimer's Disease
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Phase 3 Alzheimer's Disease Trial, Recruiting

NCT03848312
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are aged 65 or older at the time of signing consent
  • People who can speak and understand English or Spanish
  • People who have enough physical ability to use a computer for exercises (such as touching a screen or using a mouse)
  • People who can read from a computer screen at a normal viewing distance
  • People who can hear and understand a regular conversation
  • People who do not show signs of mild memory problems or dementia, based on a standard memory test score of 26 or higher (the Montreal Cognitive Assessment)
  • People who do not have a self-reported mental health condition that would get in the way of taking part in or benefiting from the study
  • People who are willing and able to complete all study activities for the full length of the trial

Who may not be able to join:

  • People who are currently taking part in another clinical trial, treatment study, or research study that tests or measures thinking and memory
  • People who have previously taken part in a study about cognitive (thinking and memory) training
  • People who report vision, hearing, or physical difficulties that would make it hard to complete the study activities
  • People who have a self-reported diagnosis of mild cognitive impairment, dementia, stroke, traumatic brain injury, brain tumour, or a neurological condition that affects thinking (such as Parkinson's disease or multiple sclerosis), or any unstable medical condition that may soon affect thinking or daily functioning (such as heart failure, severe lung disease requiring oxygen, or currently receiving chemotherapy or radiation)
  • People who are currently taking medications typically prescribed for dementia, such as Namenda, Memantine, Namzaric, Donepezil, Aricept, Rivastigmine, Exelon, Razadyne, Galantamine, Reminyl, aducanumab, or Aduhelm
  • People who have completed 10 or more hours of a computerised brain training program in the past 5 years, such as Lumosity, Posit Science Brain Fitness, InSight, Brain HQ, Lace, CogMed, CogniFit, Happy Neuron, Elevate, or Dakim
  • People with severe depressive symptoms, based on a standard depression screening score of 5 or higher (the Geriatric Depression Scale)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 727-873-4415

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
University of South Florida
Registry
ClinicalTrials.gov
Start date
19 February 2019
Est. completion
31 January 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of mild cognitive impairment or dementia

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov