Early Phase 1 Prostate Cancer Trial, Recruiting NCT03861676 Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Condition: Prostate Cancer
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Early Phase 1 Prostate Cancer Trial, Recruiting

NCT03861676
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer)
  • People whose general health and ability to carry out daily activities meets a certain standard (confirm with trial site)
  • People whose cancer is at an early clinical stage, with no confirmed spread to nearby lymph nodes or distant parts of the body
  • People whose cancer scores between 6 and 7 on the Gleason scale, which measures how aggressive the cancer appears under a microscope
  • People whose prostate is smaller than 60cc in volume, as measured by MRI or ultrasound
  • People whose urinary symptom score is 20 or below on a standard questionnaire called the IPSS
  • People who are able to undergo a specific type of PET scan (called DCF-Pyl PSMA PET) before treatment begins
  • People who have signed the study consent form before registering for the trial

Who may not be able to join:

  • People who have previously had radiation therapy to the pelvic area
  • People with serious medical or mental health conditions that, in the opinion of the treating doctor, would prevent them from completing treatment or attending follow-up appointments
  • People who have an implanted device or object that would block the ability to see implanted sources on X-ray imaging
  • People with certain metal implants in their body, severe claustrophobia that cannot be managed with medication, or any other known reason they cannot safely have an MRI scan
  • People who have been diagnosed with another type of cancer within the past 3 years

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Daniel Song, MD, Johns Hopkins University

Phone: (410) 502-5875

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
3 August 2023
Est. completion
1 December 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percent tumor coverage

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov