Motor Neurone Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any race or ethnicity, male or female
• People who do not currently have any symptoms of ALS or a related condition called fronto-temporal dementia
• People who have already had genetic testing that found a gene linked to ALS
• People who have a parent, sibling, or child who is a confirmed carrier of a gene linked to ALS
• People who have a parent, sibling, or child who has or had ALS with a confirmed related gene mutation, or who come from a family with multiple ALS diagnoses and a known related gene mutation
• People considered by the study team to be at high risk of carrying an ALS-related gene mutation, based on a review of family history and genetic information
• People who are willing to have genetic analysis done, with the choice of whether or not to be told the results
• People who are able to travel to Columbia University Irving Medical Center every 6 to 24 months for study visits
• People who are able to understand and agree to the study procedures, or who have a legally authorised representative who is able to do this on their behalf

Who may not be able to join:

• People with a known diagnosis of HIV (this applies to the part of the study involving biological sample collection)
• People with a known diagnosis of hepatitis B (this applies to the part of the study involving biological sample collection)
• People with a known diagnosis of hepatitis C (this applies to the part of the study involving biological sample collection)

Important: Always verify eligibility with the trial site directly before applying.