Phase 2 Eating Disorders Trial, Recruiting NCT03875378 Sponsor: Pouneh K. Fazeli, MD Condition: Eating Disorders
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Phase 2 Eating Disorders Trial, Recruiting

NCT03875378
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are female
  • You are between 19 and 45 years old
  • You have been diagnosed with anorexia nervosa according to standard psychiatric guidelines (DSM-5)
  • Your body weight is below 85% of what is considered ideal for your height
  • Your menstrual periods have stopped (amenorrhea)
  • A bone density scan has shown your bones are thinner than normal (a T-score below -1.0 at the spine or hip)

Who may not be able to join:

  • You have a condition known to affect bone health, such as untreated thyroid problems, vitamin D deficiency, Cushing's syndrome, diabetes, or reduced kidney function
  • You have a personal history of blood clots in your veins or arteries
  • You have had a stroke or heart attack
  • You have a condition that causes your blood to clot too easily
  • You or a close blood relative (parent, sibling, or child) has had breast cancer
  • You have a history of a condition called hereditary angioedema (a disorder causing episodes of swelling)
  • You are currently taking, or have recently taken, certain medications that affect bone health — including steroids, certain contraceptive injections, or bone-strengthening drugs called bisphosphonates (confirm with trial site for exact timeframes)
  • You have had a bone fracture in the past 12 months
  • Recent blood tests show certain abnormal results, including low potassium, abnormal liver enzyme levels, or low red blood cell levels (confirm with trial site)
  • Your fasting blood fat (triglyceride) level is above a certain level
  • You are pregnant, breastfeeding, or hoping to become pregnant in the next 18 months
  • You are currently misusing alcohol or drugs
  • Your blood test shows an abnormally high level of a hormone called PTH (parathyroid hormone)
  • Your vitamin D level is too low (below 20 ng/mL on a blood test)
  • Your blood phosphorus level is too low

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Pouneh Fazeli, MD, University of Pittsburgh

Phone: 412-586-9700

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Pouneh K. Fazeli, MD
Registry
ClinicalTrials.gov
Start date
28 August 2020
Est. completion
31 August 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in bone mineral density at 18 months

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov