Phase 2 Lymphoma Trial, Recruiting NCT03936153 Sponsor: Xynomic Pharmaceuticals, Inc. Condition: Lymphoma
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Phase 2 Lymphoma Trial, Recruiting

NCT03936153
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a specific type of blood cancer called diffuse large B-cell lymphoma (DLBCL), confirmed through laboratory testing of tissue samples
  • People who have received exactly two prior standard treatment courses for DLBCL, which must have included an anti-CD20 antibody therapy and a chemotherapy-type treatment
  • People whose cancer did not respond to their most recent treatment, or whose cancer has come back or worsened after their most recent treatment
  • People who have at least one measurable area of cancer that can be seen on a scan
  • People who have a general health and activity level rated between 0 and 2 on a standard medical scale (meaning able to carry out at least some daily activities) (confirm with trial site)
  • People whose blood counts and liver and kidney function meet specific levels as defined by the trial (confirm with trial site)

Who may not be able to join:

  • People whose lymphoma started in or has spread to the brain or spinal cord, or who have certain other specific subtypes of lymphoma, including transformed lymphoma, primary effusion lymphoma, or plasma lymphoma
  • People who are still experiencing side effects from previous cancer treatments that have not yet resolved
  • People who have an active infection that is not under control, or who need antibiotic treatment given through a drip
  • People who have received certain treatments — including steroids, chemotherapy, targeted therapy, radiation, or antibody-based therapy — within a recent period specified by the trial (confirm with trial site for exact timeframes)
  • People who are unable to swallow tablets, or who have significant digestive system problems that may affect how the study drug is absorbed
  • People who have had a stem cell transplant (either their own cells or a donor's cells) within a timeframe specified by the trial (confirm with trial site)
  • People who have an active graft-versus-host reaction (a complication that can occur after a donor stem cell transplant)
  • People who have had a major surgical procedure within the last month
  • People with evidence of HIV or hepatitis C virus infection
  • People with certain heart conditions as defined by the trial (confirm with trial site)
  • People who have a history of any other cancer besides DLBCL

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Yuankai SHI, Prof, Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phone: (01186)13716386801

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Xynomic Pharmaceuticals, Inc.
Registry
ClinicalTrials.gov
Start date
20 January 2020
Est. completion
31 July 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Clinical effect by evaluating the objective response rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov