Phase 3 Heart Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older who have had a specific type of heart attack (called a STEMI) and arrived for treatment within 6 hours of symptoms starting, with at least 20 minutes of chest pain or shortness of breath and a confirmed abnormal heart tracing (ECG) matching Australian National Heart Foundation guidelines
• People who are willing and able to follow all study requirements, including treatments, assessments, and clinic visits
• People who are able to read and understand the participant information form and provide written, signed, and dated consent to take part
• People who received a metal drug-coated stent (a small tube used to open a blocked artery) during their heart procedure
• People who agree to have heart MRI scans done 3–7 days after leaving hospital and again at 6 months

Who may not be able to join:

• People who have previously had heart bypass surgery
• People who have a significant narrowing (50% or more) in another part of the same heart artery being treated
• People who have had a previous heart attack in the same area of the heart being treated
• People who have conditions that make clot-dissolving medicines unsafe, such as a history of stroke, recent brain surgery, active internal bleeding, a brain tumour or blood vessel abnormality in the brain, uncontrolled high blood pressure, or a known bleeding disorder
• People who have conditions that make a specific heart pressure test (using a medicine called adenosine) unsafe, such as certain heart rhythm problems, moderate to severe breathing conditions like asthma, or certain types of heart block
• People diagnosed with cancer that has spread to other parts of the body
• People with a serious illness, such as a severe infection, that could make it unsafe to go through the study procedures
• People with serious medical or psychiatric (mental health) conditions that may make it difficult to follow the study plan
• People who are pregnant, breastfeeding, or not using reliable contraception; women of childbearing age must have a negative pregnancy test within 7 days before joining; men must be surgically sterilised or use a barrier method of contraception (double if required)
• People who have taken part in another research study in the past 30 days
• People in the MRI part of the study who have conditions making contrast MRI scans unsafe, such as severe claustrophobia, pregnancy, a pacemaker, certain non-MRI-safe metal implants in the brain, a defibrillator, or significantly reduced kidney function (confirm with trial site)
• People who received a specific type of blood-thinning medication (called GpIIb/IIIa inhibitors) before a certain heart pressure measurement was taken during their procedure
• People whose blocked artery was not severe enough to require the heart procedure, or who did not have the procedure for other reasons

Important: Always verify eligibility with the trial site directly before applying.