Prostate Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with prostate adenocarcinoma (a specific type of prostate cancer), confirmed by a tissue sample
• People with an early-stage prostate cancer (T1–T2b based on a specific staging system) with a cancer aggressiveness score (Gleason score) of 6 or 7 (3+4), or a Gleason score of 7 (4+3) with a recent PSA blood test result below 10 ng/mL
• People with a recent PSA blood test result below 15 ng/mL — or, for Gleason 7 (4+3), below 10 ng/mL — taken within the last 30 days (with specific timing rules if certain prostate medications were recently stopped — confirm with trial site)
• People with a urinary symptom score below 16 on a standard questionnaire (International Prostate Symptom Score)
• People whose prostate gland measures less than 80cc in volume
• People with a good general health and activity level, assessed within the 60 days before registration (rated 0–1 on a standard scale used in clinical trials)
• People aged 18 or older
• People who are able to give their informed consent before the study begins

Who may not be able to join:

• People who have chosen another treatment for their prostate cancer, such as surgery or active surveillance (watchful waiting)
• People with a history of another invasive cancer (other than certain minor skin cancers) or blood/lymph cancers, unless there has been no sign of disease for at least 5 years — people with certain non-invasive (in situ) cancers may still be considered eligible, except those with any history of bladder cancer (confirm with trial site)
• People with evidence that cancer has spread to distant parts of the body
• People whose cancer has spread to nearby lymph nodes
• People who have previously had radical prostate surgery (prostatectomy), cryosurgery, or high-intensity focused ultrasound (HIFU) for prostate cancer
• People who have previously had pelvic radiation therapy, prostate brachytherapy (internal radiation), or surgical removal of both testicles
• People who have previously had hormone therapy for prostate cancer, including certain injections, tablets, or surgical castration
• People who have taken the medication finasteride within the 30 days before registration
• People who have taken the medication dutasteride within the 90 days before registration
• People who have had or are currently receiving chemotherapy for prostate cancer
• People with serious active health conditions, including any of the following:
  • Unstable chest pain (angina) or heart failure that required hospitalisation in the past 6 months
  • A major heart attack in the past 6 months
  • An active bacterial or fungal infection currently being treated with intravenous antibiotics
  • A severe breathing condition or lung illness currently requiring hospitalisation or that would prevent participation in the study
  • Significant liver disease causing visible jaundice or serious problems with blood clotting (note: people taking blood-thinning medications such as Coumadin are not excluded)
  • A diagnosis of AIDS as defined by current public health guidelines (note: HIV testing is not required to join — confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.