Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women between 18 and 70 years old
• People whose imaging showed a single tumour, or multiple tumours that could all be removed through one section of the breast
• People who had breast-conserving surgery (where only part of the breast is removed) with clear margins, meaning no cancer cells were found at the edges of what was removed
• People who had a sentinel lymph node biopsy or underarm lymph node removal, following specific surgical guidelines depending on the results
• People whose tumour site was marked with small clips that can be seen on treatment planning scans
• People whose cancer has been confirmed by laboratory testing to be invasive breast cancer
• People whose cancer stage has been confirmed as T1–T3, N0–N3, M0 (confirm with trial site for what this means in individual cases)
• People who had specific laboratory tests after surgery to check hormone receptor and protein status of the tumour (ER, PR, HER2, Ki67)
• People with no cancer spread to distant parts of the body
• People with no cancer spread to the lymph nodes above the collarbone or behind the breastbone
• People who did not receive chemotherapy before surgery
• People who are considered medically suitable for radiation therapy after surgery
• People with a general health performance score of 80 or above on the KPS scale, which indicates a reasonable level of daily functioning (confirm with trial site)
• People who have signed a consent form agreeing to take part

Who may not be able to join:

• People with T4 or M1 stage breast cancer, meaning the cancer has grown extensively locally or spread to other parts of the body
• People with cancer spread to lymph nodes above the collarbone or behind the breastbone
• People whose laboratory results showed only a non-invasive type of breast cancer (called DCIS) with no invasive component
• People with cancer in both breasts, or a history of invasive breast cancer in the other breast
• People who received chemotherapy or hormone-blocking therapy before surgery
• People with multiple tumours that could not all be removed through a single section of the breast
• People with areas of concern in either breast that were not removed during surgery, such as suspicious calcium deposits, unusual tissue densities, or lumps that can be felt
• People with a general health performance score of 70 or below on the KPS scale
• People with serious heart or lung conditions that are not related to cancer
• People who have had, or currently have, another type of cancer, except for certain common skin cancers (basal cell or squamous cell carcinoma)
• People who have previously had radiation treatment to the chest wall or nearby lymph node areas
• People with certain medical conditions that make radiation therapy unsafe, such as systemic lupus erythematosus or cirrhosis of the liver
• People who are pregnant or breastfeeding
• People whose circumstances suggest they would not be able to complete radiation treatment or attend follow-up appointments
• People who are unable or unwilling to sign a consent form

Important: Always verify eligibility with the trial site directly before applying.