Peripheral Arterial Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
Primary group:
- People attending the Leicester Vascular Institute with a condition called severe limb ischaemia (SLI), which is serious reduced blood flow to a limb
Frailty & Cognitive assessments (additional group):
- People already in the primary group who have been scheduled for a procedure to treat their condition
- People aged 65 or older
Heart MRI assessments (additional group):
- People already in the primary group who have been scheduled for a procedure to treat their condition
Biomarker assessments (additional group):
- People already in the primary group who have been scheduled for a procedure to treat their condition
Who may not be able to join:
Primary group:
- People whose severe limb ischaemia is not caused by blocked or narrowed arteries (peripheral arterial occlusive disease)
- People who have already had a procedure done during their first hospital visit before being enrolled in the trial
- People who are unable to give consent for themselves and have no family member, partner, or friend available to help make that decision on their behalf
- People who are unable to read, write, or understand English
- People with a serious illness or condition that could put them at risk from taking part, or that could affect the trial results or their ability to participate
Heart MRI assessments:
- People with certain medical implants or conditions that make MRI scanning unsafe, such as pregnancy, certain types of pacemakers, implanted heart defibrillators, certain ear or brain implants, severe claustrophobia, or unstable chest pain (confirm with trial site)
- People who cannot receive the MRI contrast dye, due to a known reaction to it or severely reduced kidney function
- People who are unable to give their own consent for the MRI assessment
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Rob D Sayers, MD, University of Leicester
Phone: +44 (0)116 252 3141
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
12 month amputation rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.